Select features based on Coefficient of Variation from matrix — select_features_cov

Computes the Coefficient of Variation (COV) for each feature in an omics dataset from a MultiDataSet object, and select features with the highest COV values.

Usage

select_features_cov_matrix(
  mat,
  to_keep_n = NULL,
  to_keep_prop = NULL,
  with_ties = TRUE
)

Arguments

mat: Matrix of omics measurement, with features as rows and samples as columns.
to_keep_n: Integer, the number of features to retain in the dataset. Should be less than the number of features in the dataset. If NULL or NA, to_keep_prop will be used instead.
to_keep_prop: Numeric, the proportion of features to retain in the dataset. Will be ignored if to_keep_n is supplied. Value should be > 0 and < 1.
with_ties: Should ties be kept together? If TRUE, may return more features than requested. Default value is TRUE.

Value

A tibble with columns feature_id, cov and selected (logical, indicates whether the feature is selected based on its COV value). In addition, the name of the dataset filtered is stored in the return object attribute dataset_name (which can be accessed via attr(res, "dataset_name")).